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Purpose: demonstrate how to
Example: find journal articles to reactions where an actonide-type protecting group is removed from a terminal 1,2 diol in the presence of a primary hydroxyl group which has been protected with any silyl group (RCH2O-Si).
Tip: to easily draw the products, use the lasso tool 
to select the reactants, then copy and paste.
Use the eraser and other drawing tools to make the needed changes in the products.
Screen should look something like the following:
Now, use the Reaction Arrow button 
to note which are reactants and which are products.
Note that this only works if you have drawn the reactants on the left and the products on the right.
Otherwise, you may use the reaction roles button 
to assign roles.
to indicate that a particular atom in the reactant becomes a particular atom in the product. It should look similar to following:
Next, select the Get Reactions button.
Choose the "substructure of more complex structures" option and then select OK.
Following is one of the reaction results that the search found (approximately 87 reactions and 23 literature references as of August 2005).
Note: these results may not include every reported occurence of this transformation in Chemical Abstracts or the literature. This SciFinder Scholar reaction searches only selected reactions from the articles it indexes. For more complete coverage, also try a Beilstein protecting group search - see UM Science Library's Beilstein Protecting Group Reaction Search Guide for details. Where thoroughness is essential, you should also consider a SciFinder Scholar structure/substructure search on the desired product, limit results to preparations, and browse the results.
For suggestions or additional chemistry literature research assistance contact David R. Peck (webpage).
