Brian H. Clarkson, Ph.D., M.S., L.D.S.;
Mary Rafter, B.D.Sc., M.S.:
Emerging Methods in Prevention of Dental Caries

1. Does the partitioning of calcium from phosphate and fluoride in toothpastes increase the remineralization of demineralized enamel or dentin, or increase the resistance to demineralization of these tissues to a greater extent than a non-partitioned toothpaste containing the same ingredients at similar concentrations?
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2. Is lased enamel or dentin more or less susceptible to demineralization compared to non-lased enamel and dentin?
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3. Do fluoride releasing dental materials increase the remineralization of demineralized (carious) human enamel or dentin, or increase the resistance to demineralization (caries) of these tissues?
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4. Can bone morphogenic proteins, in particular BMP-7 (Op-1), be used to stimulate pulpal cells to produce new dentin (i.e. tubular dentin) in human, animal or in vitro studies? 
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The main page for this site is located at http://www.lib.umich.edu/dentlib/nihcdc/ and is maintained by the University of Michigan Dentistry Library (dentistry.library@umich.edu) in partnership with the National Institutes of Health, National Institute of Dental and Craniofacial Research. Please see also the Consensus Development Program pages, and in particular the NIH Consensus Development Conference on Caries. Copyright © 2000 Regents of the University of Michigan. All rights reserved. URL of current page: http://www.lib.umich.edu/dentlib/nihcdc/searches/clarkson/ Last Update: 10:32 AM EST on Monday, December 31, 2007