Database: EMBASE <: international biomedical and pharmaceutical literature, 1988 - May 2000. [Trial access until 3/2001. Feedback welcome to medical.library@umich.edu] Search Strategy (You Saved Citations 1-24 From Set 76): ----------------------------------------------------------------------------- 1 exp Tooth demineralization/ 7492 2 demineralization.mp. 879 3 caries.mp. 1798 4 caires.mp. 0 5 craies.mp. 0 6 careis.mp. 1 7 carise.mp. 0 8 (teeth adj3 cavit:).mp. 32 9 (tooth adj3 cavit:).mp. 97 10 (dental adj3 cavit:).mp. 85 11 (dentin adj3 cavit:).mp. 19 12 (enamel adj3 cavit:).mp. 10 13 (teeth adj3 decay:).mp. 58 14 (tooth adj3 decay:).mp. 58 15 (dental adj3 decay:).mp. 47 16 (dentin adj3 decay:).mp. 0 17 (enamel adj3 decay:).mp. 1 18 (active adj decay).mp. 5 19 (rampant adj3 decay:).mp. 4 20 (recurrent adj3 decay:).mp. 5 21 (white adj spot:).mp. 231 22 carious.mp. 109 23 cariology.ti,ab. 2 24 (non-cavitated adj3 lesion:).mp. 0 25 (noncavitated adj3 lesion:).mp. 1 26 Tooth remineralization/ 788 27 (dental adj3 fissure:).mp. 14 28 (tooth adj3 fissure:).mp. 8 29 (teeth adj3 fissure:).mp. 1 30 caries-free.mp. 29 31 cariesfree.mp. 0 32 Cariogenic agents/ 3 33 precavit:.mp. 2 34 (filled adj3 teeth).mp. 45 35 (filled adj3 tooth).mp. 9 36 (oral adj fissure:).mp. 17 37 (tooth adj3 remineraliz:).mp. 1 38 (teeth adj3 remineraliz:).mp. 5 39 dft.mp. 542 40 dfs.mp. 980 41 dmf:.mp. 1235 42 cariogeni:.mp. 164 43 or/1-42 12313 44 Sweetening agents/ 477 45 exp Oligosaccharides/ 57656 46 exp Monosaccharides/ 44854 47 exp Carbonated beverages/ 15998 48 Rehydration solutions/ 808 49 sugar:.mp. 17925 50 sucrose:.mp. 12255 51 disaccharide:.mp. 3028 52 monosaccharide:.mp. 2253 53 fructose:.mp. 6772 54 glucose:.mp. 93040 55 HFCS.mp. 64 56 "corn syrup:".mp. 52 57 sweet:.mp. 3171 58 confection:.mp. 164 59 honey:.mp. 1921 60 candy.mp. 124 61 candies.mp. 34 62 "sports drink:".mp. 31 63 maltose:.mp. 2732 64 polysaccharide:.mp. 10172 65 oligosaccharide:.mp. 10241 66 trisaccharide:.mp. 1085 67 hexose:.mp. 2244 68 fucose:.mp. 2155 69 galactose:.mp. 8040 70 mannose:.mp. 6893 71 rhamnose:.mp. 849 72 sorbose:.mp. 182 73 exp Dietary carbohydrates/ 946 74 or/44-73 171111 75 43 and 74 661 76 limit 75 to (human and english language) 324 77 from 76 keep 1-300 300 78 from 76 keep 301-324 24 *************************** <1> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89200343 AU Soderling E. Makinen KK. Chen C-Y. Pape HR Jr. Loesche W. Makinen P-L. IN School of Dentistry, University of Michigan, Ann Arbor, MI; United States of America. TI Effect of sorbitol, xylitol, and xylitol/sorbitol chewing gums on dental plaque. SO Caries Research. Vol 23(5) (pp 378-384), 1989. <2> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89200337 AU Grenby TH. Phillips A. Mistry M. IN Department of Oral Medicine, Guy's Hospital, United Medical and Dental Schools, London SE1 9RT; United Kingdom. TI Studies of the dental properties of lactitol compared with five other bulk sweeteners in vitro. SO Caries Research. Vol 23(5) (pp 315-319), 1989. <3> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89179352 AU Kolenbrander PE. IN Laboratory of Microbial Ecology, National Institute of Dental Research, National Institutes of Health, Bethesda, MD 20892; United States of America. TI Intergeneric coaggregation among human oral bacteria and ecology of dental plaque. SO Annual Review of Microbiology. Vol 42 (pp 627-656), 1988. <4> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89159757 AU Giertsen E. Scheie AA. Rolla G. IN Department of Pedodontics and Caries Prophylaxis, Faculty of Dentistry, University of Oslo, N-0455 Oslo 4; Norway. TI In vivo effects of zinc and chlorhexidine on dental plaque ureolysis and glycolysis. SO Journal of Dental Research. Vol 68(6) (pp 1132-1134), 1989. <5> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89120834 AU Tolo K. Millar S. Shlossman M. Genco RJ. IN Department of Periodontology, University of Oslo, Oslo; Norway. TI Antigens released from four oral bacteria in periodontitis. SO Immunological Investigations. Vol 18(1-4) (pp 171-185), 1989. AB Antigens fractionated from cultures of four oral bacteria were tested for binding of serum IgG, IgA and IgM from patients in early and established phases of periodontitis. Bacteroides gingivalis and A. actinomycetemcomitans released antigens that discriminated between serum from individuals with or without periodontitis. The discriminating antigens ranged from 10 to 43 kDa and included neutral sugar and protein but no lipids. Significantly increased levels of IgG and IgA antibodies to the antigens released from B. gingivalis were detected before bone loss was seen and predicted such disease progression. <6> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89112788 AU Corbin SB. IN National Institutes of Health, National Institute of Dental Research, Bethesda, MD 20892; United States of America. TI Fluoridation then and now. SO American Journal of Public Health. Vol 79(5) (pp 561-563), 1989. <7> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89107153 AU Wiggins J. Geddes DM. IN Brompton Hospital, London SW3 6HP; United Kingdom. TI Respiratory aspects of Shwachman's syndrome in adults. SO European Respiratory Journal. Vol 2(3) (pp 285-288), 1989. AB Shwachman's Syndrome is a rare disorder which causes considerable morbidity in childhood and can be confused with cystic fibrosis. Six patients (4 males; mean age 27 yrs) are described in order to illustrate the clinical picture of the syndrome in adults. Recognized features persisting in later life include pancreatic insufficiency and bone marrow dysfunction (all patients), short stature (5/6), advanced dental caries (4/6), and impaired glucose tolerance (2/6). Chest radiograph was normal in all patients whilst lung function tests showed mild restriction in three and obstruction in two. All patients were cyclically neutropenic (nadir count 2.1 x 109.l-1). Four of the six patients were thrombocytopenic and three had persistent immunoglobulin deficiencies. Neutrophil chemotaxis was abnormal in four patients and the nitro blue tetrazolium test was abnormal in fifth. Two patients suffered from recurrent respiratory infections, one of whom died from bone marrow aplasia. Although Shwachman's Syndrome may be less troublesome in adults than in children, many of the abnormalities persist into adult life and may continue to cause diagnostic difficulty. <8> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89087038 AU Broderick E. Mabry J. Robertson D. Thompson J. IN Area Dental Services Branch, Oklahoma City Area Indian Health Service, Oklahoma City, OK; United States of America. TI Baby bottle tooth decay in native American children in head start centers. SO Public Health Reports. Vol 104(1) (pp 50-54), 1989. AB Baby bottle tooth decay is a unique pattern of dental caries (tooth decay) affecting the dentition of young children. It is associated with the practice of putting the child to sleep with a nursing bottle filled with liquid that contains sugar. Practitioners who treat Native American children have noted that this population suffers from a high prevalence of the condition. In order to establish specific program priorities and treatment needs for this segment of the Native American population, additional information is required on both prevalence and severity of baby bottle tooth decay. In this survey, an overall prevalence of 70 percent was observed when Navajo and Cherokee Head Start students ages 4-5 years were examined. Of the children affected by baby bottle tooth decay, 87 percent displayed the most severe manifestation of the disease. The prevalence of this disease in these Native American children appears to be substantially higher than in other populations. Futher study is needed to identify the factors contributing to this difference in prevalence and to identify effective measures for reducing the occurrence of baby bottle tooth decay among Native Americans. <9> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89028789 AU Eke PI. Rotimi VO. Laughon BE. IN Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos; Nigeria. TI Coaggregation of black-pigmented Bacteroides species with other oral bacteria. SO Journal of Medical Microbiology. Vol 28(1) (pp 1-4), 1989. AB Coaggregation of Bacteroides gingivalis and other black-pigmented bacteroides with several oral bacteria was studied with 'reagent' strains specially prepared by methods that have been described previously. B. gingivalis coaggregated with Veillonella, Capnocytophaga and Actinomyces spp., but not with any Streptococcus spp. Coaggregation of B. gingivalis with other bacteria was inhibited and reversed by lactose. Of the asaccharolytic black-pigmented bacteroides, only B. gingivalis demonstrated any coaggregation with other bacteria, whereas within the saccharolytic species, B. loescheii showed a marked ability to coaggregate with several species of oral bacteria. This property of coaggregation by B. gingivalis may be an important factor in the pathogenesis of periodontal infections. <10> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89004388 AU Nilsson U. Oste R. Jagerstad M. Birkhed D. IN Department of Applied Nutrition, Chemical Center, University of Lund, S-221 00 Lund; Sweden. TI Cereal fructans: In vitro and in vivo studies on availability in rats and humans. SO Journal of Nutrition. Vol 118(11) (pp 1325-1330), 1988. AB The bioavailability of cereal fructans (fructo-oligosaccharides) was investigated both in vitro and in vivo. In vitro studies indicated very slow hydrolysis by human gastric juice and by homogenate of the intestinal mucosa (rat). After intubation of fructans into the stomachs of rats, the recovery of fructans in the small intestine and colon was approximately the same as that of an unabsorbed marker (polyethylene glycol), indicating no or very low disappearance of fructans in the small intestine. In vivo studies of the small intestine in rats showed that the rate of disappearance of fructans was lower than that of mannose, which is known to be absorbed through passive diffusion. In addition the cariogenic effect of cereal fructans was compared to that of glucose. Acid formation from low molecular-weight fructans was found in human dental plaque in vitro. A mouth rinse with unfractionated fructans, containing some quantities of sucrose, fructose and glucose, resulted in relatively low pH values in human plaque in vivo, even if the decrease in pH was somewhat less pronounced when compared with a mouth rinse with glucose. <11> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 89003893 AU Yamamoto T. IN Kishiwada Tokushukai Hospital, Kishiwada, Osaka 596; Japan. TI A case of active acromegaly with reduced height and type 1 renal tubular acidosis. SO Endocrinologia Japonica. Vol 35(1) (pp 165-170), 1988. AB A 41-year-old man with acromegaly was suffering from chronic, progressive backache and aware of reduction in this body height. Endocrine studies revealed increased glucose non-suppressible serum growth hormone (GH) and serum prolactin (PRL). Pituitary microadenoma was detected by a computerized axial tomogram and subsequently resected by trans-sphenoidal adenomectomy. The tumor proved to be a mixed GH- and PRL-secreting adenoma by electron microscopy and immunoperoxidase staining. Concurrent investigation of backache and reduced height disclosed markedly reduced radiodensity of the spinal bones, bilateral nephrocalcinosis, and hypercalciuria, which were ascribed to renal tubular acidosis (RTA) demonstrated by reduced urinary excretion of acids and insufficient reduction of urinary pH following oral administration of ammonium chloride. From the analogy to certain endocrinopathies, it appears likely that enhanced calcium metabolism and resultant hypercalciuria due to excess GH and PRL have led to the development of RTA, which further enhanced calciuria. Such enhanced calcium metabolism and consequent hypercaliuria conceivably led to accelerated demineralization of the spine and resulted in the reduced height of this patient in his early forties. <12> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88264283 AU Rugg-Gunn AJ. IN Department of Oral Biology, University of Newcastle Dental School, Newcastle upon Tyne NE2 4BW; United Kingdom. TI Effect of Lycasin upon plaque pH when taken as a syrup or as a boiled sweet. Short communication. SO Caries Research. Vol 22(6) (pp 375-376), 1988. <13> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88256967 AU Shah N. IN Department of Dental Surgery, All India Institute of Medical Sciences, New Delhi 110029; India. TI Fluorides in dental health: Recent concepts. SO Indian Journal of Pediatrics. Vol 55(5) (pp 693-701), 1988. <14> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88229461 AU Lesan WR. IN Department of Dental Surgery, University of Nairobi, Nairobi; Kenya. TI Dental fluorosis: A review of literature with comments on tropical characteristics. SO East African Medical Journal. Vol 64(7) (pp 493-498), 1987. <15> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88223961 AU Krause K-H. IN Neurologische Universitatsklinik, Heidelberg; Germany. TI Side effects of antiepileptic drugs in long term treatment. SO Klinische Wochenschrift. Vol 66(13) (pp 601-604), 1988. AB 610 epileptics of the Heidelberg out-patient clinic for convulsive disorders aged between 20 and 40 years and under long-term anticonvulsant therapy were examined to investigate possible influences of medication (i.e. type, total amount, daily dose and serum level of antiepileptic drugs as well as duration of therapy) on clinical signs and symptoms, anamnestically reported disturbances, anthropometric data, neurographic parameters, concentration performance (d2-test), bone density (Norland-Cameron bone mineral analyzer) and a variety of hematochemical parameters, including enzymes, haematological parameters, electrolytes, renal parameters, uric acid, glucose, bilirubin, lipids, immunoglobulins, vitamins and hormones. Most of the laboratory results were compared to data obtained from a normal population of the same age group and the same geographical region. <16> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88209344 AU Phillipou G. Seaborn CJ. Phillips PJ. IN Endocrine and Diabetes Laboratory, The Queen Elizabeth Hospital, Woodville, SA 5011; Australia. TI Re-evaluation of the fructosamine reaction. SO Clinical Chemistry. Vol 34(8) (pp 1561-1564), 1988. AB The difference in spectral characteristics between 1-deoxy-1-morpholinofructose (DMF) and protein/plasma samples in the fructosamine reaction has been related to the solubility of the diformazan formed by reduction of nitro blue tetrazolium chloride. Addition of the surfactant Triton X-100 (20 g/L) to the reagent buffer not only corrects this anomaly but also enhances the absolute response. Detailed investigation of DMF and dihydroxyacetone as calibration standards for the reaction established a clear preference for the latter. Fundamental differences in reaction kinetics were also noted between the Amadori rearrangement products of glucose formed from morpholine (DMF) or the amino lysine groups of protein (glycated albumin). From the reactivity of dihydroxyacetone, as well as glyceraldehyde, observed in the fructosamine reaction, and the presence of this class of compounds (trioses) in human plasma, we infer that they may also contribute to the differentiation of diabetic and non-diabetic samples. <17> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88144887 AU Makinen KK. Isokangas P. IN Department of Biologic and Material Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48109; United States of America. TI Relationship between carbohydrate sweeteners and oral diseases. SO Progress in Food & Nutrition Science. Vol 12(1) (pp 73-109), 1988. <18> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88120604 AU Grenby TH. Wells JC. IN Department of Oral Medicine and Pathology, UMDS, Guy's Hospital, London SE1 9RT; United Kingdom. TI Dental effects of infants' fruit drinks. SO Lancet. Vol 1(8592) (pp 992), 1988. <19> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88115697 AU Keevil CW. Bradshaw DJ. Dowsett AB. Feary TW. IN Pathogenic Microbes Research Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury SP4 0JG; United Kingdom. TI Microbial film formation: Dental plaque deposition on acrylic tiles using continuous culture techniques. SO Journal of Applied Bacteriology. Vol 62(2) (pp 129-138), 1987. <20> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88115117 AU Razak IA. Jaafar N. IN Department of Preventive Dentistry, Dental Faculty, University of Malaya, 59100 Kuala Lumpur; Malaysia. TI A correlation study of sweet preference and caries severity. SO J PEDODONTICS, Vol 12(3) (pp 275-280), 1988. <21> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88108627 AU Toth Z. Zimmermann P. Banoczy J. Szombath D. IN Department of Conservative Dentistry, Faculty of Dentistry, Semmelweis Medical University, H-1088 Budapest; Hungary. TI Enamel biopsy studies after five years consumption of fluoridated milk. SO FLUORIDE-QUART REP, Vol 20(4) (pp 171-176), 1987. AB Enamel biopsy examination from incisor teeth of 41 institutionalized children, aged eight to ten years, who had consumed fluoridated milk for five years, showed a significant increase in enamel fluoride content (12.54 +/- 0.761 ng), compared with data from 47 control children (7.30 +/- 0.360 ng). The amount of dissolved calcium was lower in the test group (4.57 +/- 0.511 mug), than in controls (5.60 +/- 0.533 mug). These data agree with the results of clinical investigations, demonstrating a considerable reduction in caries prevalence and DMF mean values. <22> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88059723 AU Curzon MEJ. Alemi Z. Duggal MS. IN Department of Child Dental Health, School of Dentistry, University of Leeds, Leeds LS2 9LU; United Kingdom. TI Sugars in baby and infants' drinks. SO Lancet. Vol 1(8584) (pp 539-540), 1988. <23> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88044034 AU Brouwer ID. Backer Dirks O. De Bruin A. Hautvast JGAJ. IN Department of Human Nutrition, Agricultural University, 6703 BC Wageningen; Netherlands. TI Unsuitability of World Health Organisation guidelines for fluoride concentrations in drinking water in Senegal. SO Lancet. Vol 1(8579) (pp 223-225), 1988. AB A survey was done of the prevalence of dental fluorosis among children aged 7-16 years and the occurrence of skeletal fluorosis among adults aged 40-60 years living in regions in Senegal where fluoride concentrations in the drinking water ranged from < 0.1 to 7.4 mg/l. In the area where the fluoride concentration in the drinking water was 1.1 mg/l milder forms of dental fluorosis were found, the prevalence being 68.5%. In areas where fluoride concentrations exceeded 4 mg/l the prevalence of dental fluorosis reached 100%. Kyphosis was very prevalent among a community whose drinking water contained 7.4 mg/l fluoride. Radiographs of the vertebral column, hand, and wrist of 3 adults with kyphosis confirmed the diagnosis of skeletal fluorosis. High sweat loss and a high intake of water because of the hot weather may account for the finding. The present World Health Organisation guideline for the upper limit of fluoride concentration in drinking water may be unsuitable for countries with a hot, dry climate. <24> *COPYRIGHT ELSEVIER SCIENCE B.V. 1994 - ALL RIGHTS RESERVED* AN 88006964 AU World Health Organization, Geneva. TI Prevention of oral diseases. SO WHO Offset Publication. Issue 103 (pp 1-83), 1987. AB It is clear that combating oral disease mainly by increasing manpower and by improving treatment systems has not achieved the desired levels of oral health despite ever-increasing expenditure. This book promotes the far more successful preventive approach which can be implemented in countries at all levels of development. The three most important preventive measures are oral hygiene, optimal use of fluorides, and dietary control of sugars. Personal oral hygiene is the single most effective measure for periodontal disease prevention, and it also has an important role in caries prevention since fluorides can also be applied through personal care. Whereas community water fluoridation programmes require a certain technological sophistication, self care is effective, available to all, and thus of greater importance globally to improved oral health. The whole area of health education and promotion aimed at optimizing self-care and minimizing intervention is of prime importance in reinforcing the message offered by this book. The aim of this book is to provide oral health administrators and other personnel working with oral disease preventive programmes with a simple but comprehensive guide for their everyday work, from the design of a programme through to its evaluation. The objectives of this book are: to introduce the essential elements of the planning process, including manpower planning and costing; to encourage administrators to select appropriate preventive measures for their communities; to encourage planners and oral health personnel to evaluate and compare their results; to review current preventive programmes in given communities with a view to improving and extending them. This book is focused on primary prevention, as this is the most effective and desirable type of prevention, though some associated aspects of secondary or tertiary prevention are also included. This book, deals only with preventive programmes that are relevant to sizeable community problems and for which demonstrable improvements are attainable. Thus, it does not deal with genetic counselling for facial clefts or dentofacial anomalies, or with limitation of habits not clearly associated with oral diseases or conditions.